19.3.11

Assignment #1


This is our Fundamental Facts about Gene Regulation assignment. I found that while completing it, there were concepts from first year, and even high school, that I had to review before this class! Nevertheless, it was a good start to the course. 
Q&A:
Qa, b, c: labelled on diagram
Qd: RNA polymerase complex will dissociate from the DNA at the end of an exon when the newly synthesized RNA molecule forms a G-C-rich hairpin loop followed by a run of Us, or in eukaryotes, where the 3’ end is polyadenylated.
Qe: Translation will start and stop at the start/stop codon of the mRNA
Qf: Proteins that are needed for transcription include RNA polymerase, transcription factors such as TFIID (transcription factor), helicase, TATA-binding protein, activators, repressors, Rho for termination
Qg: Some cis-regulatory elements that have been omitted from the diagram include a frameshift element that regulates alternative frame use with mRNAs and IRES (internal ribosome entry site) which initiates translation in the middle of an RNA. 

Amanda
email: manda147@interchange.ubc.ca | Student Number: 92681071 
 

15.3.11

About me :)

Hi Dr. Kalas & whoever may be reading this,

This is my blog for my individual portfolio that I'll be putting together. A little bit about myself:
I'm in my 4th year at UBC, and my major is Integrated Science where I chose to do Microbiology and Medical Genetics. I'll be graduating this year (exciting/scary!) and hopefully attending grad school preferably doing a project in regards to genetics and cancer, as I want to work in oncology or cancer research eventually. I chose to take BIOL 463 to further my understanding of gene regulation and the elements that are necessary for proper functionality of all these genes that control us. It has been a great class and has definitely shed some new light on gene regulation, especially in embryogenesis, that I can apply to my other studies and in the future. I hope to share a bit of what I learned this semester through this blog, and hope you enjoy it!

Amanda
email: manda147@interchange.ubc.ca | Student Number: 92681071